A customer was looking to achieve a higher level of containment in their dry granulation process as the drug they produce is highly potent and hazardous to operators. Critical to the success of the project was preserving containment during the charging, discharging and cleaning processes.
Fitzpatrick and Extract Technology collaborated to bring their top-quality equipment together to create the perfect solution for the customer. A Fitzpatrick CCS320 was integrated into an Extract Technology containment Isolator to deliver operator protection of <1 µg/m³.
The CCS320 was perfect for the project as it is the most compact Roll Compactor on the market and all the process parts are on the front making them easier to access.
Rapid Transfer Ports (RTPs) are used to safely deliver fresh powder and take out the granules.
By design the CCS320 is a very well-sealed and safe machine, complying to OEB 3 & 4 containment levels, but the addition of the isolator enabled OEB 4 & 5 to be reached. This delivered a safety guarantee for the customers’ operators but also ensured the surrounding area remained clean and contamination-free.
This aligned design has meant that full containment can be achieved at all times – even during the loading and transferring stages. Furthermore, when cleaning the equipment, this containment is preserved and the operators are able to dismantle the CCS safely through the glove ports.
If you are interested in finding out more – download the Case Study or contact one of our team to discuss how you could achieve enhanced contained systems.