Dry Granulation

Dry granulation is the most Lean, efficient method for conditioning powders. Compared to wet granulation it uses less equipment and processing steps and is unlikely to damage the ingredients.

With Wet Granulation the batch size must match the machine's minimum and maximum fill capacities.

What is Dry Granulation?

Dry Granulation (sometimes referred to as precompression or double compression) is a continuous manufacturing process that eliminates the need for additional time spent constructing batch sizes.

The process compacts powders into larger pieces or rolls, that can be granulated (broken down) into a dosage form, often leading to a tablet manufacturing activity.

With fewer process variables it is simpler to validate, optimize and scale.  The Dry Granulation approach is a truly lean and straightforward way to condition powders. Dry granulation is a well established method that can help you improve your processing versatility by enabling more efficient manufacturing.

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Improve your powder handling and materials processing with dry granulation processing

Dry Granulation Method

The simplest way to condition powders.

Dry Granulation using a Roll Compaction Machine is the process of compacting primary particles into larger granules in order to: 

  • lock in blend ratios to prevent segregation later in the manufacturing process.
  • improve powder flow so that conveying and feeding into downstream processes are trouble-free eliminating caking and bridging.
  • condition powders prior to further downstream processing, such as enhancing compressibility for the tablet pressing stage.
  • control particle hardness and provide granule integrity during conveying and processing steps.
  • create granular material that will dissolve or disperse most effectively.
  • densify materials to reduce bulk density during storage, transport and packing.
  • control dust and reduce environmental risk, waste and cross-contamination.



Compact particles using Roller Compaction
Download the CCS Roller Compactor Brochure

Related Resources

CCS Roll Compactor Range

Find out how the CCS range of Roll Compactors
could be the solution to your dry granulation
needs by downloading our brochure today.

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Control the parameters of Dry Granulation

Roll Compaction involves feeding powder between two counter-rotating rolls, where it is pressed together to create a dense, compact ribbon which is then milled to achieve a uniform particle size. 

Efficient Roller Compaction using Fitzpatrick CCS

By controlling the following parameters on the Roll Compactor it is possible to generate the ideal powder for your process needs:

  • Feed system design & speed
  • Roll dimensions – diameter & width
  • Roll speed, force & gap
  • Roll surface profile
  • Powder Compact routing
  • Mill Rotor design & velocity
  • Mill Screen type & hole size

Learn more about Fitzpatrick's High Containment Dry Granulation Machines.

Dry Granulation Applications that we support

Fitzpatrick have a customer base across the world and therefore gain knowledge of a wide range of industry applications where our Roller Compaction technology is used. Typical applications include:


Dry Granulation - best practice resources and advice