Dry granulation is the most Lean, efficient method for conditioning powders. Compared to wet granulation it uses less equipment and processing steps and is unlikely to damage the ingredients.
With Wet Granulation the batch size must match the machine's minimum and maximum fill capacities.
Dry Granulation (sometimes referred to as precompression or double compression) is a continuous manufacturing process that eliminates the need for additional time spent constructing batch sizes.
The process compacts powders into larger pieces or rolls, that can be granulated (broken down) into a dosage form, often leading to a tablet manufacturing activity.
With fewer process variables it is simpler to validate, optimize and scale. The Dry Granulation approach is a truly lean and straightforward way to condition powders. Dry granulation is a well established method that can help you improve your processing versatility by enabling more efficient manufacturing.
The simplest way to condition powders.
Dry Granulation using a Roll Compaction Machine is the process of compacting primary particles into larger granules in order to:
Roll Compaction involves feeding powder between two counter-rotating rolls, where it is pressed together to create a dense, compact ribbon which is then milled to achieve a uniform particle size.
By controlling the following parameters on the Roll Compactor it is possible to generate the ideal powder for your process needs:
Learn more about Fitzpatrick's High Containment Dry Granulation Machines.
Fitzpatrick have a customer base across the world and therefore gain knowledge of a wide range of industry applications where our Roller Compaction technology is used. Typical applications include:
Here are some of the companies currently using our equipment.